In this video brief from AHA 2025, Dr. Erin Bohula presents the primary results of the VESALIUS-CV trial, a phase 3 study of evolocumab in more than 12,000 patients at high cardiovascular risk but without prior myocardial infarction or stroke. She discusses the study design, primary and secondary outcomes, and implications for LDL-C lowering in primary cardiovascular prevention. Dr. Bohula also addresses the clinical significance of these findings in the context of current lipid management strategies and highlights factors that may guide patient selection in real-world settings.
Primary Results of the VESALIUS-CV Trial: Evolocumab in Patients at High Cardiovascular Risk Without Prior MI or Stroke

Transcript
Primary Results of the VESALIUS-CV Trial: Evolocumab in Patients at High Cardiovascular Risk Without Prior MI or Stroke
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Overview
Provider(s)/Educational Partner(s)

Today’s healthcare environment is constantly evolving and advances of medical science occur at an accelerating pace. CME/CE plays an important role in the clinical environment and is an essential element of physician training, learning, and improvement, thereby importantly contributing to optimal patient care. Since 2000, MEDCON’s mission is to deliver high quality within the world of medical education by creating forums like PACE-CME, organizing live meetings, and providing online education. We aim to stimulate the review, exchange, and assimilation of key scientific findings to improve patients’ health, to raise awareness of new science underlying various disease states, and to accelerate the translation of this information into clinical practice.Commercial Support
This activity is supported by an independent educational grant from Amgen, Inc.
videoEvolocumab in Patients at High Cardiovascular Risk Without Prior MI or Stroke: Primary Results of the VESALIUS-CV Trial
Show more
videoGlobal Burden of Stroke and Myocardial Infarction in Patients at High Risk of First MACE: Insights From the VESALIUS-REAL Study
Show more
videoReal-World Impact of Evolocumab on MACE Reduction in ASCVD
Show more
Overview
In this video brief from AHA 2025, Dr. Erin Bohula presents the primary results of the VESALIUS-CV trial, a phase 3 study of evolocumab in more than 12,000 patients at high cardiovascular risk but without prior myocardial infarction or stroke. She discusses the study design, primary and secondary outcomes, and implications for LDL-C lowering in primary cardiovascular prevention. Dr. Bohula also addresses the clinical significance of these findings in the context of current lipid management strategies and highlights factors that may guide patient selection in real-world settings.
Provider(s)/Educational Partner(s)

Today’s healthcare environment is constantly evolving and advances of medical science occur at an accelerating pace. CME/CE plays an important role in the clinical environment and is an essential element of physician training, learning, and improvement, thereby importantly contributing to optimal patient care. Since 2000, MEDCON’s mission is to deliver high quality within the world of medical education by creating forums like PACE-CME, organizing live meetings, and providing online education. We aim to stimulate the review, exchange, and assimilation of key scientific findings to improve patients’ health, to raise awareness of new science underlying various disease states, and to accelerate the translation of this information into clinical practice.Commercial Support
This activity is supported by an independent educational grant from Amgen, Inc.
videoEvolocumab in Patients at High Cardiovascular Risk Without Prior MI or Stroke: Primary Results of the VESALIUS-CV Trial
Show more
videoGlobal Burden of Stroke and Myocardial Infarction in Patients at High Risk of First MACE: Insights From the VESALIUS-REAL Study
Show more
videoReal-World Impact of Evolocumab on MACE Reduction in ASCVD
Show more
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